-- PeptiDream (TYO:4587) said its partner Asahi Kasei Therapeutics has started a Phase 1 clinical trial of AK1940, a TNFR1 inhibitor discovered using its peptide platform, according to a Monday filing on the Tokyo Stock Exchange.
The candidate targets autoimmune diseases and showed efficacy in preclinical studies, the company said.
PeptiDream will receive a milestone payment and is eligible for further payments and royalties tied to development and sales.
MSC Industrial Direct (MSM) shares were up 5.4% in Monday afternoon trading after KeyBanc upgraded its rating on the company's stock to overweight from sector weight and set a $117 price target.Trading volume exceeded 843,000 shares, compared with a daily average of nearly 646,000.Price: $103.07, Change: $+5.24, Percent Change: +5.36%
CrowdStrike (CRWD) shares were up about 1.6% in Monday trading after Mizuho upgraded the stock to outperform from neutral and boosted its price target to $520 from $490.Trading volume stood at more than 1.4 million shares, compared with a daily average of about 4.2 million.Price: $455.31, Change: $+7.18, Percent Change: +1.60%
Domino's Pizza (DPZ) has an average rating of overweight and mean price target of $459.09, according to analysts polled by FactSet.(covers equity, commodity and economic research from major banks and research firms in North America, Asia and Europe. Research providers may contact us here: https://www..com/contact-us)Price: $335.23, Change: $-32.96, Percent Change: -8.95%